The Municipality of San Enrique is politically subdivided into 28 barangays. Each barangay consists of puroks and some have sitios.
- Abaca
- Asisig
- Bantayan
- Braulan
- Cabugao Nuevo
- Cabugao Viejo
- Camiri
- Compo
- Catan-Agan
- Cubay
- Dacal
- Dumiles
- Garita
- Gines Nuevo
- Imbang Pequeño
- Imbesad-an
- Iprog
- Lip-ac
- Madarag
- Mapili
- Paga
- Palje
- Poblacion Ilawod
- Poblacion Ilaya
- Quinolpan
- Rumagayray
- San Antonio
- Tambunac